Michela, Rosini: search on Z-Library

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1

Curcumin in Alzheimer’s disease: Can we think to new strategies and perspectives for this molecule?

Maria, Serafini Melania, Michele, Catanzaro, Michela, Rosini, Marco, Racchi, Cristina, Lanni

Journal:

Pharmacological Research

Year:

2017

Language:

english

File:

PDF, 832 KB

english, 2017

2

Noninvasive Stimulation of Prefrontal Cortex Strengthens Existing Episodic Memories and Reduces Forgetting in the Elderly

Sandrini, Marco, Brambilla, Michela, Manenti, Rosa, Rosini, Sandra, Cohen, Leonardo G., Cotelli, Maria

Journal:

Brain Stimulation

Year:

2017

Language:

english

File:

PDF, 73 KB

english, 2017

3

Polypharmacology: the rise of multitarget drugs over combination therapies

Rosini, Michela

Journal:

Future Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 803 KB

english, 2014

4

Memantine Derivatives as Multitarget Agents in Alzheimerâs Disease

Marotta, Giambattista, Basagni, Filippo, Rosini, Michela, Minarini, Anna

Journal:

Year:

2020

File:

PDF, 4.97 MB

2020

5

Rational Approach To Discover Multipotent Anti-Alzheimer Drugs

Rosini, Michela, Andrisano, Vincenza, Bartolini, Manuela, Bolognesi, Maria L., Hrelia, Patrizia, Minarini, Anna, Tarozzi, Andrea, Melchiorre, Carlo

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 75 KB

english, 2005

6

Increase of Theta/Gamma and Alpha3/Alpha2 Ratio is Associated with Amygdalo-Hippocampal Complex Atrophy

Moretti, Davide Vito, Pievani, Michela, Fracassi, Claudia, Binetti, Giuliano, Rosini, Sandra, Geroldi, Cristina, Zanetti, Orazio, Rossini, Paolo M., Frisoni, Giovanni B.

Journal:

Journal of Alzheimer's Disease

Year:

2009

Language:

english

File:

PDF, 70 KB

english, 2009

7

Noninvasive stimulation of prefrontal cortex strengthens existing episodic memories and reduces forgetting in the elderly

Sandrini, Marco, Brambilla, Michela, Manenti, Rosa, Rosini, Sandra, Cohen, Leonardo G., Cotelli, Maria

Journal:

Frontiers in Aging Neuroscience

Year:

2014

Language:

english

File:

PDF, 741 KB

english, 2014

8

Inhibition of Acetylcholinesterase, β-Amyloid Aggregation, and NMDA Receptors in Alzheimer’s Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush

Simoni, Elena, Bartolini, Manuela, Cavalli, Andrea, Ceccarini, Luisa, Pascu, Nicoleta, McClymont, David W., Rosini, Michela, Tarozzi, Andrea, Bolognesi, Maria L., Minarini, Anna

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 152 KB

english, 2008

9

Heterocyclic inhibitors of AChE acylation and peripheral sites

Maria Laura Bolognesi, Vincenza Andrisano, Manuela Bartolini, Andrea Cavalli, Anna Minarini, Maurizio Recanatini, Michela Rosini, Vincenzo Tumiatti, Carlo Melchiorre

Journal:

Year:

2005

Language:

english

File:

PDF, 411 KB

english, 2005

10

Polyamines May Modulate Both G Protein-Coupled Receptors and G Proteins

Gabriella Marucci, Francesca Novi, Rita Banzi, Maria L. Bolognesi, Michela Buccioni, Anna Minarini, Michela Rosini, Piero Angeli, Roberto Maggio, Carlo Melchiorre

Journal:

Medicinal Chemistry Research

Year:

2004

File:

PDF, 462 KB

2004

11

NRF2 and PPAR-Î³ Pathways in Oligodendrocyte Progenitors: Focus on ROS Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation

De Nuccio, Chiara, Bernardo, Antonietta, Troiano, Carmen, Brignone, Maria Stefania, Falchi, Mario, Greco, Anita, Rosini, Michela, Basagni, Filippo, Lanni, Cristina, Serafini, Melania Maria, Minghetti,

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 2.83 MB

2020

12

Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update

Tumiatti, Vincenzo, Bolognesi, Maria Laura, Minarini, Anna, Rosini, Michela, Milelli, Andrea, Matera, Riccardo, Melchiorre, Carlo

Journal:

Expert Opinion on Therapeutic Patents

Year:

2008

Language:

english

File:

PDF, 320 KB

english, 2008

13

Controlled iontophoretic delivery in vitro and in vivo of ARN14140 – a multi-target compound for Alzheimer’s disease

Singhal, Mayank, Merino, Virginia, Rosini, Michela, Cavalli, Andrea, Kalia, Yogeshvar N.

Journal:

Molecular Pharmaceutics

Year:

2019

Language:

english

File:

PDF, 1.69 MB

english, 2019

14

Polymethylene tetraamine backbone as template for the development of biologically active polyamines

Carlo Melchiorre, Alessandra Antonello, Rita Banzi, Maria Laura Bolognesi, Anna Minarini, Michela Rosini, Vincenzo Tumiatti

Journal:

Medicinal Research Reviews

Year:

2003

Language:

english

File:

PDF, 382 KB

english, 2003

15

Structure–activity relationship and site of binding of polyamine derivatives at the nicotinic acetylcholine receptor

M. Gabriele Bixel, Michael Krauss, Ying Liu, Maria L. Bolognesi, Michela Rosini, Ian S. Mellor, Peter N. R. Usherwood, Carlo Melchiorre, Koji Nakanishi, Ferdinand Hucho

Journal:

Year:

2000

Language:

english

File:

PDF, 1.20 MB

english, 2000

16

Structure−Activity Relationships of Methoctramine-Related Polyamines as Muscular Nicotinic Receptor Noncompetitive Antagonists. 3.1 Effect of Inserting the Tetraamine Backbone into a Macrocyclic Structure

Angeli, Piero, Antonello, Alessandra, Rosini, Michela, Tumiatti, Vincenzo, Hucho, Ferdinand, Bolognesi, Maria L., Bixel, M. Gabriele, Marucci, Gabriella, Bartolini, Manuela, Krauss, Michael

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 130 KB

english, 2002

17

Structure−Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Further Investigation on the Inner Spacer

Tumiatti, Vincenzo, Milelli, Andrea, Minarini, Anna, Rosini, Michela, Bolognesi, Maria Laura, Micco, Marialuisa, Andrisano, Vincenza, Bartolini, Manuela, Mancini, Francesca, Recanatini, Maurizio, Cava

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 110 KB

english, 2008

18

The Bivalent Ligand Approach as a Tool for Improving the in vitro Anti-Alzheimer Multitarget Profile of Dimebon

Rosini, Michela, Simoni, Elena, Bartolini, Manuela, Soriano, Elena, Marco-Contelles, José, Andrisano, Vincenza, Monti, Barbara, Windisch, Manfred, Hutter-Paier, Birgit, McClymont, David W., Mellor, Ia

Journal:

Year:

2013

Language:

english

File:

PDF, 640 KB

english, 2013

19

Oxidative Stress in Alzheimer’s Disease: Are We Connecting the Dots?

Rosini, Michela, Simoni, Elena, Milelli, Andrea, Minarini, Anna, Melchiorre, Carlo

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1003 KB

english, 2014

20

Modulation of Keap1/Nrf2/ARE Signaling Pathway by Curcuma- and Garlic-Derived Hybrids

Serafini, Melania Maria, Catanzaro, Michele, Fagiani, Francesca, Simoni, Elena, Caporaso, Roberta, Dacrema, Marco, Romanoni, Irene, Govoni, Stefano, Racchi, Marco, Daglia, Maria, Rosini, Michela, Lann

Journal:

Frontiers in Pharmacology

Year:

2020

File:

PDF, 1.37 MB

2020

21

Design, Synthesis, and Biological Evaluation of Symmetrically and Unsymmetrically Substituted Methoctramine-Related Polyamines as Muscular Nicotinic Receptor Noncompetitive Antagonists

Rosini, Michela, Budriesi, Roberta, Bixel, M. Gabriele, Bolognesi, Maria L., Chiarini, Alberto, Hucho, Ferdinand, Krogsgaard-Larsen, Povl, Mellor, Ian R., Minarini, Anna, Tumiatti, Vincenzo, Usherwood

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 479 KB

english, 1999

22

Structure−Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 2. Role of the Substituents on the Phenyl Ring and Nitrogen Atoms of Caproctamine

Tumiatti, Vincenzo, Rosini, Michela, Bartolini, Manuela, Cavalli, Andrea, Marucci, Gabriella, Andrisano, Vincenza, Angeli, Piero, Banzi, Rita, Minarini, Anna, Recanatini, Maurizio, Melchiorre, Carlo

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 258 KB

english, 2003

23

Targeting the Nrf2/Amyloid-Beta Liaison in Alzheimer’s Disease: A Rational Approach

Simoni, Elena, Serafini, Melania M., Caporaso, Roberta, Marchetti, Chiara, Racchi, Marco, Minarini, Anna, Bartolini, Manuela, Lanni, Cristina, Rosini, Michela

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 2.08 MB

english, 2017

24

ChemInform Abstract: Exploiting the Lipoic Acid Structure in the Search for Novel Multitarget Ligands Against Alzheimer′s Disease.

Michela Rosini, Elena Simoni, Manuela Bartolini, Andrea Tarozzi, Riccardo Matera, Andrea Milelli, Patrizia Hrelia, Vincenza Andrisano, Maria Laura Bolognesi, Carlo Melchiorre

Journal:

Year:

2012

File:

PDF, 22 KB

2012

25

Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics

Anna Minarini, Gabriella Marucci, Cristina Bellucci, Gianluca Giorgi, Vincenzo Tumiatti, Maria Laura Bolognesi, Riccardo Matera, Michela Rosini, Carlo Melchiorre

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 379 KB

english, 2008

26

Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer’s disease

Michela Rosini, Elena Simoni, Manuela Bartolini, Andrea Tarozzi, Riccardo Matera, Andrea Milelli, Patrizia Hrelia, Vincenza Andrisano, Maria Laura Bolognesi, Carlo Melchiorre

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 291 KB

english, 2011

27

Hexahydrochromeno[4,3- b ]pyrrole Derivatives as Acetylcholinesterase Inhibitors

Bolognesi, Maria L., Andrisano, Vincenza, Bartolini, Manuela, Minarini, Anna, Rosini, Michela, Tumiatti, Vincenzo, Melchiorre, Carlo

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 56 KB

english, 2001

28

Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase IIα

Minniti, Elirosa, Byl, Jo Ann W., Riccardi, Laura, Sissi, Claudia, Rosini, Michela, De Vivo, Marco, Minarini, Anna, Osheroff, Neil

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 1.52 MB

english, 2017

29

Design, Synthesis, and Biological Evaluation of Prazosin-Related Derivatives as Multipotent Compounds

Antonello, Alessandra, Hrelia, Patrizia, Leonardi, Amedeo, Marucci, Gabriella, Rosini, Michela, Tarozzi, Andrea, Tumiatti, Vincenzo, Melchiorre, Carlo

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 72 KB

english, 2005

30

Hybrid Lipoic Acid Derivatives to Attack Prion Disease on Multiple Fronts

Salvatore Bongarzone, Hoang Ngoc Ai Tran, Prof. Andrea Cavalli, Prof. Marinella Roberti, Dr. Michela Rosini, Prof. Paolo Carloni, Prof. Giuseppe Legname, Prof. Maria Laura Bolognesi

Journal:

Year:

2011

Language:

english

File:

PDF, 257 KB

english, 2011

31

Nature-Inspired Multifunctional Ligands: Focusing on Amyloid-Based Molecular Mechanisms of Alzheimer's Disease

Simoni, Elena, Serafini, Melania M., Bartolini, Manuela, Caporaso, Roberta, Pinto, Antonella, Necchi, Daniela, Fiori, Jessica, Andrisano, Vincenza, Minarini, Anna, Lanni, Cristina, Rosini, Michela

Journal:

Year:

2016

Language:

english

File:

PDF, 1.20 MB

english, 2016

32

Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase

Di Paolo, Maria Luisa, Cervelli, Manuela, Mariottini, Paolo, Leonetti, Alessia, Polticelli, Fabio, Rosini, Michela, Milelli, Andrea, Basagni, Filippo, Venerando, Rina, Agostinelli, Enzo, Minarini, Ann

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 3.56 MB

english, 2019

33

Functionalized Cannabinoid Subtype 2 Receptor Ligands: Fluorescent, PET, Photochromic and Covalent Molecular Probes

Basagni, Filippo, Rosini, Michela, Decker, Michael

Journal:

Year:

2020

File:

PDF, 5.13 MB

2020

34

Reversible human serum albumin binding of lipocrine: A circular dichroism study

Carlo Bertucci, Angela De Simone, Marco Pistolozzi, Michela Rosini

Journal:

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

35

Alzheimer's disease: new approaches to drug discovery

Maria L Bolognesi, Riccardo Matera, Anna Minarini, Michela Rosini, Carlo Melchiorre

Journal:

Current Opinion in Chemical Biology

Year:

2009

Language:

english

File:

PDF, 309 KB

english, 2009

36

Structure−Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 3. Effect of Replacing the Inner Polymethylene Chain with Cyclic Moieties

Tumiatti, Vincenzo, Andrisano, Vincenza, Banzi, Rita, Bartolini, Manuela, Minarini, Anna, Rosini, Michela, Melchiorre, Carlo

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 145 KB

english, 2004

37

Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities

Maria Laura Bolognesi, Manuela Bartolini, Francesca Mancini, Gianpaolo Chiriano, Luisa Ceccarini, Michela Rosini, Andrea Milelli, Vincenzo Tumiatti, Vincenza Andrisano, Carlo Melchiorre

Journal:

Year:

2010

Language:

english

File:

PDF, 319 KB

english, 2010

38

Monobenzylether of (R,R)-1,2-diphenylethane-1,2-diol as chiral auxiliary in the diastereoselective reduction of α-ketoesters

Stefano Superchi, Michela Contursi, Carlo Rosini

Journal:

Year:

1998

Language:

english

File:

PDF, 394 KB

english, 1998

39

Quinazoline based α 1 -adrenoreceptor antagonists with potent antiproliferative activity in human prostate cancer cell lines

Maestri, Valentina, Tarozzi, Andrea, Simoni, Elena, Cilia, Antonio, Poggesi, Elena, Naldi, Marina, Nicolini, Benedetta, Pruccoli, Letizia, Rosini, Michela, Minarini, Anna

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 929 KB

english, 2017

40

Analogues of Prazosin That Bear a Benextramine-Related Polyamine Backbone Exhibit Different Antagonism toward α 1 -Adrenoreceptor Subtypes

Bolognesi, Maria L., Marucci, Gabriella, Angeli, Piero, Buccioni, Michela, Minarini, Anna, Rosini, Michela, Tumiatti, Vincenzo, Melchiorre, Carlo

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 130 KB

english, 2001

41

Functionalized Cannabinoid Subtype 2 Receptor Ligands: Fluorescent, PET, Photochromic and Covalent Molecular Probes

Basagni, Filippo, Rosini, Michela, Decker, Michael

Journal:

Year:

2020

File:

PDF, 1.22 MB

2020

42

ChemInform Abstract: Hexahydrochromeno[4,3-b]pyrrole Derivatives as Acetylcholinesterase Inhibitors.

Maria L. Bolognesi, Vincenza Andrisano, Manuela Bartolini, Anna Minarini, Michela Rosini, Vincenzo Tumiatti, Carlo Melchiorre

Journal:

Year:

2001

File:

PDF, 26 KB

2001

43

Methoctramine analogues inhibit responses to capsaicin and protons in rat dorsal root ganglion neurons

Ian R. Mellor, Jane Ogilvie, Florentina Pluteanu, Richard H. Clothier, Terence L. Parker, Michela Rosini, Anna Minarini, Vincenzo Tumiatti, Carlo Melchiorre

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 419 KB

english, 2004

44

Multi-target-Directed Ligands To Combat Neurodegenerative Diseases

Cavalli, Andrea, Bolognesi, Maria Laura, Minarini, Anna, Rosini, Michela, Tumiatti, Vincenzo, Recanatini, Maurizio, Melchiorre, Carlo

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.49 MB

english, 2008

45

WB 4101-Related Compounds. 2. 1 Role of the Ethylene Chain Separating Amine and Phenoxy Units on the Affinity for α 1 -Adrenoreceptor Subtypes and 5-HT 1A Receptors

Bolognesi, Maria L., Budriesi, Roberta, Cavalli, Andrea, Chiarini, Alberto, Gotti, Roberto, Leonardi, Amedeo, Minarini, Anna, Poggesi, Elena, Recanatini, Maurizio, Rosini, Michela, Tumiatti, Vincenzo,

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 272 KB

english, 1999

46

Polyamines in Drug Discovery: From the Universal Template Approach to the Multitarget-Directed Ligand Design Strategy

Melchiorre, Carlo, Bolognesi, Maria Laura, Minarini, Anna, Rosini, Michela, Tumiatti, Vincenzo

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.43 MB

english, 2010

47

Prazosin-Related Compounds. Effect of Transforming the Piperazinylquinazoline Moiety into an Aminomethyltetrahydroacridine System on the Affinity for α 1 -Adrenoreceptors

Rosini, Michela, Antonello, Alessandra, Cavalli, Andrea, Bolognesi, Maria L., Minarini, Anna, Marucci, Gabriella, Poggesi, Elena, Leonardi, Amedeo, Melchiorre, Carlo

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 158 KB

english, 2003

48

Efficacy of semantic–phonological treatment combined with tDCS for verb retrieval in a patient with aphasia

Manenti, Rosa, Petesi, Michela, Brambilla, Michela, Rosini, Sandra, Miozzo, Antonio, Padovani, Alessandro, Miniussi, Carlo, Cotelli, Maria

Journal:

Year:

2015

Language:

english

File:

PDF, 333 KB

english, 2015

49

Multitarget-Directed Ligands: Innovative Chemical Probes and Therapeutic Tools Against Alzheimer's Disease

Laura Bolognesi, Maria, Simoni, Elena, Rosini, Michela, Minarini, Anna, Tumiatti, Vincenzo, Melchiorre, Carlo

Journal:

Current Topics in Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 348 KB

english, 2011

50

Design, Synthesis and Biological Evaluation of Ambenonium Derivatives as AChE Inhibitors.

Maria Laura Bolognesi, Andrea Cavalli, Vincenza Andrisano, Manuela Bartolini, Rita Banzi, Alessandra Antonello, Michela Rosini, Carlo Melchiorre

Journal:

Year:

2004

File:

PDF, 84 KB

2004

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